Acanthamoeba spp., amoebae that live in water and soil, can hitch a ride on a contact lens, then invade a vulnerable eye and destroy the cornea.
Acanthamoeba (pronounced ah-canth-ah-me-baa) literally means spiny amoeba, and that’s exactly what Acanthamoeba spp. are—single celled amoebae that produce spiny pseudopodia as they move slowly along. About five times the size of a human red blood cell, acanthamoebae are large as microbes go, but still much too small to be seen with the naked eye. The most common amoebae in fresh water and soil, Acanthamoeba spp. sometimes cause human infections.
In water, moist soil, mud, and decaying organic material, acanthamoebae feed on bacteria and other microscopic organisms. In water supply systems, these amoebae live in the biofilm of organisms that proliferate on the inside surfaces of pipes, grazing on the other organisms in the biofilm. When the environment gets dry, they wrap themselves up inside a tough cyst wall and wait for the moisture and the food to return. They’re resistant to drying, chlorine, and many antiseptics. They are tough and ubiquitous.
Though the natural environment for Acanthamoeba spp. is moist decaying organic material, at least six different species are capable of feeding on living tissue. Given the chance, these amoebae will invade human tissues and cause disease—the most common way that they do this is through the cornea of an eye from a contact lens. The destruction of the cornea, acanthamoeba keratitis, can result in the need for corneal transplant, and sometimes even surgical removal of the eye.
A rare cause of eye infections before the days of contact lenses, Acanthamoeba spp. were given a new opportunity when people started regularly putting lenses in their eyes. Tap water is usually the vehicle for the amoeba:
Even though acanthamoeba keratitis is much more common than it used to be, it is still rare even among contact lens wearers. To avoid this devastating infection:
Contact lenses and lens care disinfectants are improving; however, contact lens wearers still have to be careful. Taking the precautions listed above should keep this opportunistic amoeba where it belongs—in the environment.
A Parasite in the Blood Supply
Drisdelle, Rosemary. “Preventing Infections with Proper Lens Care.” Optical Prism. Mar (2007): 32-36.
Drisdelle, Rosemary. “The Amoeba that Loves Eyes.” Optical Prism. March (2004): 24-26.
Roberts, Larry S. and John Janovy Jr. Foundations of Parasitology 6th Ed. Boston: McGraw Hill, 2000.